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 Formulary Chapter 4: Central nervous system - Full Chapter
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04.09.01  Expand sub section  Dopaminergic drugs used in Parkinsons disease
04.09.01  Expand sub section  Dopamine receptor agonists
04.09.01  Expand sub section  Levodopa
04.09.01  Expand sub section  Monoamine-oxidase-B inhibitors
04.09.01  Expand sub section  Catachol-O-methyltransferase inhibitors to top
Entacapone (Comtess®)
(Tablet)
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Formulary
Advice
 
   
Tolcapone (Tasmar®)
(Tablet)
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Restricted Drug Restricted
Red Hospital

  • CUHFT: For use by Consultant Neurologists and Geriatricians ONLY.

  • Non-formulary at all other Trusts and in Primary Care

  • Regular LFT monitoring required

  • Previously withdrawn due to liver problems. Relaunched August 2005.

 
   
Opicapone
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Restricted Drug Restricted
Red Hospital

 

  • NWAFT only (HOSPITAL ONLY): For use when patients cannot be stabilised on entacapone and does not meet the criteria below in relation to persistent diarrhoea.
  • Specialist Initiation (CUHFT and NWAFT) 2-month trial by secondary care for continuation in primary care only For patients with Parkinson’s and motor fluctuations who are eligible for a 2 month trial of opicapone will necessarily first have had a trial of entacapone, and will have experienced the unacceptable adverse effect of persistent diarrhoea causing incontinence, or frequent passing of loose stool disturbing sleep or lifestyle, as defined by Bristol stool chart 6/7, which resolves when stopping entacapone.
  • Non-formulary at all other Trusts.
 
   
04.09.01  Expand sub section  Amantadine
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

OTC

Available Over the Counter. Consider Self Care   

Green

Formulary - Can be prescribed in both secondary and primary care.   

Advice

Formulary - Specialist Advice, secondary care advice provided for primary care initiation.  

Amber No SCG

Formulary - Specialist initiation without shared care guidance.  

Amber SCG

Formulary - Specialist initiation with shared care guidance.  

Red Hospital

Restricted - Hospital only, not to be prescribed in primary care.  

Switch

Not recommended for prescribing. Switch to alternative cost-effective option.   

Black

Not recommended for prescribing in primary or secondary care.  

Grey

Not recommended as no formal application made for addition to the formulary. Contact relevant pharmacy team for further information.   

Non Formulary

Non-Formulary (category under review).  

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