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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.10.02  Expand sub section  Fibrinolytic drugs
Streptokinase
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Formulary
Red Hospital
 
   
Alteplase
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Restricted Drug Restricted
Red Hospital

 

  • CUHFT, NWAFT and RPH: Recommended as per NICE TA264 for stroke patients presenting within 4.5 hours of the stroke and intracranial haemorrhage has been excluded by appropriate imaging techniques.
  • RPH: Also in combinations with Dornase alfa for pleurodesis. 

June 2020 - Shortage of Urokinase

  • CUHFT -  Due to a nationwide shortage of Urokinase, we are sourcing Alteplase as a temporary replacement. Internal guidance has been circulated. For further information contact pharmacy.

 





 

 

 
Link  NICE TA264: Alteplase for treating acute ischaemic stroke
Link  CUHFT Administration of alteplase (rtPA) during cardiopulmonary resuscitation (CPR) caused by pulmonary embolism (PE)
Link  CUHFT Patient Management Guide
   
Reteplase
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Restricted Drug Restricted
Red Hospital

  • CUHFT: Restricted to use by cardiologists 2nd line in acute myocardial infarction.

  • Non formulary at all other Trusts


 

 
   
Urokinase
(Injection)
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Restricted Drug Restricted
Red Hospital

 

  • NWAFT and RPH: Formulary

 

  • CUHFT: Restricted for unblocking Hickmann lines and in dialysis. Only 10,000 unit vial on Formulary.

June 2020 - Shortage of Urokinase

  • CUHFT -  Due to a nationwide shortage of Urokinase, we are sourcing Alteplase as a temporary replacement. Internal guidance has been circulated. For further information contact pharmacy.



 

 
   
Tenecteplase
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Restricted Drug Restricted
Red Hospital

  • CUHFT: Restricted to use by ambulance crew for mycardial infartion patients.

  • NWAFT and RPH: Non formulary

 
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

OTC

Available Over the Counter. Consider Self Care   

Green

Formulary - Can be prescribed in both secondary and primary care.   

Advice

Formulary - Specialist Advice, secondary care advice provided for primary care initiation.  

Amber No SCG

Formulary - Specialist initiation without shared care guidance.  

Amber SCG

Formulary - Specialist initiation with shared care guidance.  

Red Hospital

Restricted - Hospital only, not to be prescribed in primary care.  

Switch

Not recommended for prescribing. Switch to alternative cost-effective option.   

Black

Not recommended for prescribing in primary or secondary care.  

Grey

Not recommended as no formal application made for addition to the formulary. Contact relevant pharmacy team for further information.   

Non Formulary

Non-Formulary (category under review).  

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