Aspirin dispersible and EC tablets (75mg) can be purchased from a Community Pharmacist.
Pregnant women at an increased risk of preeclampsia at their booking appointment should be offered a prescription of 150mg aspirin (in some circumstances this may not be appropriate and lower doses (60-75mg) may be used (for example, women with hepatic or renal disease)) to be taken each night from 12 weeks of pregnancy until birth (off-label use):
Please note Community pharmacies cannot legally sell aspirin as a Pharmacy Only Medicine for prevention of pre-eclampsia in pregnancy in England.
People who have had an ischaemic stroke or who have peripheral arterial disease or multivascular disease (as per NICE TA210)
Following MI only if aspirin is contra-indicated or not tolerated
Proven gastro-intestinal haemorrhage with low dose aspirin.
For cardiologists to treat patients who have had an acute coronary syndrome (ACS).
Where a liquid preparation is clinically required in paediatric patients, Clopidogrel 25mg/5mL* is the standardised liquid strength which should be prescribed in children ( unlicensed):
*Clopidogrel strength is agreed, but as no monograph for this medication exists yet in the BNFC it is not yet published there.
Using standardised strengths of unlicensed liquid medicines in children, will reduce the risk of errors being made in the doses given to children and prevent hospitalisation from accidental under and overdoses.
CUHFT: Approved only for Dr. Higgins to treat FOUR patients annually for thrombo-embolic complications of neuro-surgery. All other uses at CUHFT non formulary.
NICE TA351: Cangrelor for reducing atherothrombotic events in people undergoing percutaneous coronary intervention or awaiting surgery requiring interruption of anti‑platelet therapy (terminated appraisal). No evidence submission was received from The Medicines Company.