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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.05.02  Expand sub section  Centrally acting antihypertensive drugs
Methyldopa
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Formulary
Green

 

  • Should only be used for hypertension where other agents have failed or are not suitable.
  • Methyldopa use in pregnancy:
    • Methyldopa may be indicated in the treatment of hypertension or gestational hypertension.
    • Methyldopa is not specifically licensed for the treatment of hypertension in pregnancy. However, the manufacturer states that methyldopa can be used during pregnancy if there is no safer alternative available.
    • NICE guidelines identify labetalol as the preferred antihypertensive for use during pregnancy. 
    • See links below for further information. 
 
Link  NICE CKS - Hypertension in Pregnancy (Updated October 2019)
Link  UKTIS - Use of methyldopa in pregnancy
   
Clonidine
(Injection)
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Restricted Drug Restricted
Red Hospital

  • CUHFT: Restricted for the maintenance of sedation in ICU. unlicensed unlicensed

  • NWAFT: Specialist use only

  • RPH: Restricted to

    • Hypertensive crisis.

    • Restlessness and agitation in critically ill patients. unlicensed unlicensed




See Section 4 for prophylaxis of migraine, attention deficit-hyperactivity disorder (unlicensed unlicensed) and Tourette’s syndrome (unlicensed unlicensed).

 
   
 ....
 Non Formulary Items
Clonidine
(Tablets)

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Non Formulary
Grey
  • See Section 4 for prophylaxis of migraine, attention deficit-hyperactivity disorder (unlicensed unlicensed) and Tourette’s syndrome (unlicensed unlicensed).

June 2020 - Shortage of Clonidine 25microgram tablets

  • Accord are out of stock and unable to advise a resupply date.
  • Sandoz have stock available which is being sent to wholesalers - Ethigen, Lexon and AAH. 
  • See link below for further information.
Link  June 2020: Shortage of Clonidine 25microgram tablets
 
Moxonidine

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Non Formulary
Grey
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

OTC

Available Over the Counter. Consider Self Care   

Green

Formulary - Can be prescribed in both secondary and primary care.   

Advice

Formulary - Specialist Advice, secondary care advice provided for primary care initiation.  

Amber No SCG

Formulary - Specialist initiation without shared care guidance.  

Amber SCG

Formulary - Specialist initiation with shared care guidance.  

Red Hospital

Restricted - Hospital only, not to be prescribed in primary care.  

Switch

Not recommended for prescribing. Switch to alternative cost-effective option.   

Black

Not recommended for prescribing in primary or secondary care.  

Grey

Not recommended as no formal application made for addition to the formulary. Contact relevant pharmacy team for further information.   

Non Formulary

Non-Formulary (category under review).  

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