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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.02.03  Expand sub section  Potassium-sparing diuretics and aldosterone antagonists
02.02.03  Expand sub section  Aldosterone antagonists
Spironolactone
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
  • Where a liquid preparation is clinically required in paediatric patients, Spironolactone 50mg/5mL is the standardised liquid strength which should be prescribed in children (unlicensed unlicensed):
    • Using standardised strengths of unlicensed liquid medicines in children, will reduce the risk of errors being made in the doses given to children and prevent hospitalisation from accidental under and overdoses.
    • See link below for further information.
 
Link  MHRA Drug Safety Update: Spironolactone and Renin Angiotensin Drugs Feb 2016
Link  RCPCH and NPPG Position Statement 18-01: Using Standardised Strengths of Unlicensed Liquid Medicines in Children
   
Eplerenone
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Restricted Drug Restricted
Amber No SCG

  • Second line aldosterone antagonist for controlling blood pressure when spironolactone is indicated but cannot be tolerated.

 
Link  NICE CG 108: Chronic heart failure
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

OTC

Available Over the Counter. Consider Self Care   

Green

Formulary - Can be prescribed in both secondary and primary care.   

Advice

Formulary - Specialist Advice, secondary care advice provided for primary care initiation.  

Amber No SCG

Formulary - Specialist initiation without shared care guidance.  

Amber SCG

Formulary - Specialist initiation with shared care guidance.  

Red Hospital

Restricted - Hospital only, not to be prescribed in primary care.  

Switch

Not recommended for prescribing. Switch to alternative cost-effective option.   

Black

Not recommended for prescribing in primary or secondary care.  

Grey

Not recommended as no formal application made for addition to the formulary. Contact relevant pharmacy team for further information.   

Non Formulary

Non-Formulary (category under review).  

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