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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.02.01  Expand sub section  Thiazides and related diuretics
Bendroflumethiazide
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First Choice
Green
 
Indapamide
(2.5mg tablets)
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Formulary
Green

  • 2.5 mg tablets only. MR prep is non formulary.

  • For use in patients with renal failure or those who are intolerant of bendroflumethiazide or co-amilozide.

 
   
Metolazone
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Restricted Drug Restricted
Amber No SCG

 

  • Metolazone has been withdrawn from the UK market on commercial grounds and is available on a NAMED PATIENT BASIS only. unlicensed unlicensed. It should only be prescribed when there is no suitable licensed alternative.
  • For most patients a switch to bendroflumethiazide (in combination with a loop diuretic) would be suitable and is supported by the British Society for Heart Failure.
  • Metolazone may be prescribed for renal patients when a high dose of a loop diuretic +/- another thiazide has failed to control fluid retention adequately.
  • Ongoing management and provision of the medicine will need to be discussed with the GP before initiation.
  • Please note - this medication is not commonly prescribed as a daily dose.
 
   
Chlorothiazide
(Suspension 250mg/5ml )
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Restricted Drug Restricted
Red Hospital

  • CUHFT: Suspension 250mg/5ml for paediatric use only. Available as an unlicensed import.unlicensed unlicensed

  • Non formulary at all other Trusts and in Primary Care

 
   
Chlortalidone
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Restricted Drug Restricted
Red Hospital

  • CUHFT: Formulary (may be difficult to obtain)

  • Non-formulary at all other Trusts and in Primary Care

 
Link  Chlortalidone availability- UKMI Q & A
   
Cyclopenthiazide
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Restricted Drug Restricted
Red Hospital

  • CUHFT: Restricted to Clinical pharmacologists only for exceptional circumstances. (May be difficult to obtain)

  • Non formulary at all other Trusts and in Primary Care


 

 
   
 ....
 Non Formulary Items
Indapamide MR

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Non Formulary
Grey

  • Modified release formulation is non formulary.

 
Xipamide  (Diurexan)

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Non Formulary
Grey
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

OTC

Available Over the Counter. Consider Self Care   

Green

Formulary - Can be prescribed in both secondary and primary care.   

Advice

Formulary - Specialist Advice, secondary care advice provided for primary care initiation.  

Amber No SCG

Formulary - Specialist initiation without shared care guidance.  

Amber SCG

Formulary - Specialist initiation with shared care guidance.  

Red Hospital

Restricted - Hospital only, not to be prescribed in primary care.  

Switch

Not recommended for prescribing. Switch to alternative cost-effective option.   

Black

Not recommended for prescribing in primary or secondary care.  

Grey

Not recommended as no formal application made for addition to the formulary. Contact relevant pharmacy team for further information.   

Non Formulary

Non-Formulary (category under review).  

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