For use in patients with renal failure or those who are intolerant of bendroflumethiazide or co-amilozide.
Metolazone has been withdrawn from the UK market on commercial grounds and is available on a NAMED PATIENT BASIS only. unlicensed. It should only be prescribed when there is no suitable licensed alternative.
For most patients a switch to bendroflumethiazide (in combination with a loop diuretic) would be suitable and is supported by the British Society for Heart Failure.
Metolazone may be prescribed for renal patients when a high dose of a loop diuretic +/- another thiazide has failed to control fluid retention adequately.
Ongoing management and provision of the medicine will need to be discussed with the GP before initiation.
Please note - this medication is not commonly prescribed as a daily dose.
Chlorothiazide (Suspension 250mg/5ml )
CUHFT: Suspension 250mg/5ml for paediatric use only. Available as an unlicensed import. unlicensed
Non formulary at all other Trusts and in Primary Care
CUHFT: Formulary (may be difficult to obtain)
Non-formulary at all other Trusts and in Primary Care