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 Formulary Chapter 13: Skin - Full Chapter
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13.06.01  Expand sub section  Topical preparations for acne
13.06.01  Expand sub section  Benzoyl peroxide and azelaic acid
13.06.01  Expand sub section  Topical antibacterials for acne
13.06.01  Expand sub section  Topical retinoids and related preparations for acne
Adapalene (Differin)
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Formulary
Green

(Gel 0.1%, Cream 0.1%)



  • In Primary Care - Formulary 2nd line

  • CUHFT Restricted Item Dermatologists only.

  • NWAFT - Formulary

  • Second generation retinoid, less irritant

 
Link  MHRA Letters sent to healthcare professionals in June 2019: Retinoids▼ (Acitretin, Adapalene, Alitretinoin, Bexarotene, Isotretinoin, Tretinoin, and Tazarotene) - risk of teratogenicity and neuropsychiatric disorders
   
13.06.01  Expand sub section  Other topical preparations for acne to top
 ....
 Non Formulary Items
Adapalene / Benzoyl Peroxide  (Epiduo)

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Non Formulary
Grey

  • Gel (0.1% Adapalene / 2.5% Benzoyl Peroxide)

Link  MHRA Letters sent to healthcare professionals in June 2019: Retinoids▼ (Acitretin, Adapalene, Alitretinoin, Bexarotene, Isotretinoin, Tretinoin, and Tazarotene) - risk of teratogenicity and neuropsychiatric disorders
 
Isotretinoin  (Isotrex gel)

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Non Formulary
Black

(Gel 0.05%)

Discontinued: The sole supplier have been discontinued this product. Prescribers should individually assess patients for an alternative formulary treatment

 

Link  MHRA Letters sent to healthcare professionals in June 2019: Retinoids▼ (Acitretin, Adapalene, Alitretinoin, Bexarotene, Isotretinoin, Tretinoin, and Tazarotene) - risk of teratogenicity and neuropsychiatric disorders
 
Isotretinoin with antibacterial  (Isotrexin)

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Non Formulary
Black

 

  • Gel, isotretinoin 0.05%, erythromycin 2% in ethanolic basis.
  • Discontinued: The sole supplier have been discontinued this product. Prescribers should individually assess patients for an alternative formulary treatment
Link  MHRA Letters sent to healthcare professionals in June 2019: Retinoids▼ (Acitretin, Adapalene, Alitretinoin, Bexarotene, Isotretinoin, Tretinoin, and Tazarotene) - risk of teratogenicity and neuropsychiatric disorders
 
Tretinoin with antibacterial  (Aknemycin Plus)

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Non Formulary
Grey
  • Solution, tretinoin 0.025%, erythromycin 4% in an alcoholic basis.
  • Link  MHRA Letters sent to healthcare professionals in June 2019: Retinoids▼ (Acitretin, Adapalene, Alitretinoin, Bexarotene, Isotretinoin, Tretinoin, and Tazarotene) - risk of teratogenicity and neuropsychiatric disorders
     
      
    Key
    note Notes
    Section Title Section Title (top level)
    Section Title Section Title (sub level)
    First Choice Item First Choice item
    Non Formulary Item Non Formulary section
    Restricted Drug
    Restricted Drug
    Unlicensed Drug
    Unlicensed
    Track Changes
    Display tracking information
    click to search medicines.org.uk
    Link to adult BNF
    click to search medicines.org.uk
    Link to children's BNF
    click to search medicines.org.uk
    Link to SPCs
    SMC
    Scottish Medicines Consortium
    Cytotoxic Drug
    Cytotoxic Drug
    CD
    Controlled Drug
    High Cost Medicine
    High Cost Medicine
    Cancer Drugs Fund
    Cancer Drugs Fund
    NHSE
    NHS England
    Homecare
    Homecare
    CCG
    CCG

    Traffic Light Status Information

    Status Description

    OTC

    Available Over the Counter. Consider Self Care   

    Green

    Formulary - Can be prescribed in both secondary and primary care.   

    Advice

    Formulary - Specialist Advice, secondary care advice provided for primary care initiation.  

    Amber No SCG

    Formulary - Specialist initiation without shared care guidance.  

    Amber SCG

    Formulary - Specialist initiation with shared care guidance.  

    Red Hospital

    Restricted - Hospital only, not to be prescribed in primary care.  

    Switch

    Not recommended for prescribing. Switch to alternative cost-effective option.   

    Black

    Not recommended for prescribing in primary or secondary care.  

    Grey

    Not recommended as no formal application made for addition to the formulary. Contact relevant pharmacy team for further information.   

    Non Formulary

    Non-Formulary (category under review).  

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